13. Honorificabilitudinitatibus (27 letters)
The word occurs in Shakespeare's play Love's Labour's Lost and means "with honorablenesses." It can also be viewed as a rearrangement of the Latin sentence "Hi ludi F. Baconis nati tuiti orbi," meaning: "These plays, F. Bacon's offspring, are preserved for the world." This twist has been used to support the "Baconian theory" that Francis Bacon wrote Shakespeare's plays. However, in The Shakespearean Ciphers Examined (Cambridge, England: Cambridge University Press, 1957), William F. and Elizebeth S. Friedman have similar anagrams that "prove" Theodore Roosevelt, Lewis Carroll, and Gertrude Stein also wrote Shakespeare.

12. Antidisestablishmentarianism (28 letters)
The word means, according to Funk & Wagnalls New Standard Dictionary of the English Language, "a doctrine of opposition to disestablishment (withdrawal of state patronage, support, or exclusive recognition from a church)." It is said to have been used once by British Prime Minister William Ewart Gladstone (1809 - 1898).

11. Floccinaucinihilipilification (29 letters)
This is found in the Oxford English Dictionary and means "the action or habit of estimating something as worthless."

10. Supercalifragilisticexpialidocious (34 letters)
From the movie Mary Poppins. It means "extraordinary."

9. Praetertranssubstantiationalistically (37 letters)
Used by Mark McShane in his novel "Untimely Ripped" (1963). It means the act of surpassing the act of transubstantiation, which refers specifically to the transformation of the bread and wine into the body and blood of Christ during the Roman Catholic mass.

8. Hepaticocholecystocholecystenterostomy (40 letters)
Found in Gould's Medical Dictionary. It is defined as "the surgical formation of a passage between the gall bladder and hepatic duct, on the one hand, and between the intestine and the gall bladder, on the other."

7. Pneumonoultramicroscopicsilicovolcanoconiosis (45 letters)
Found in Webster's New Collegiate Dictionary, 8th edition. It is "a pneumoconiosis caused by the inhalation of very fine silicate or quartz dust" and occurs especially in miners.

6. Antipericatametaanaparcircumvolutiorectumgustpoops of the coprofied (50 letters)
The title of a book on a shelf in a library in the classic ribald work Gargantua and Pantagruel, by Francois Rabelais.

5. Osseocarnisanguineoviscericartilagininervomedullar y (51 letters)
A term that describes the structure of the human body; it occurs in "Headlong Hall" (1861), a novel by Thomas Love Peacock.

4. Aequeosalinocalcalinoceraceoaluminosocupreovitriol ic (52 letters)
Describes the composition of the spa waters at Bristol, in Gloucestershire, England. The word was coined by an English medical writer, Dr. Edward Strother (1675 - 1737).

3. Bababadalgharaghtakamminarronnkonnbronn-tonnerronntuonnthunntrovarrhounawnskawn-toohoohoordenenthurnuk (100 letters)
This word is on the first page of "Finnegans Wake" by James Joyce and is a symbolic thunderclap representing the fall of Adam and Eve. (Other 100-letter words appear throughout the book.)

2. Lopadotemachoselachogaleokranioleipsanodrimhypotri mmatosilphiparaomelitokatakechymenokichlepikossyph ophattoperisteralektryonoptekephalliokiglopeleiola goiosiraiobaphetraganopterygon (182 letters)
The English transliteration of a Greek word that occurs in Aristophanes' play "The Ecclesiazusae." The word is defined as "a goulash composed of all the leftovers from the meals of the last two weeks." A more detailed translation is "plattero-filletomulleti-turboto-cranio-morselo-pickleo-acido-silphio-honeyo-poured on the top of theouzelo-throstleo-cushato-culvero-roastingomarrowo-dippero-levereto-syrupo-gibleto-wings."

1. (3,600 letters)
A chemical name describing bovine NADP-specific glutamate dehydrogenase, which contains 500 amino acids.

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