Dear Deepak,
It depends upon the nature of the change. The license issued under the Factories Act or any other similar Law of regulatory nature is basically a permission granted to use a particular premises for a particular purpose subject to certain norms. Therefore, when there is a cosmetic change like change in the door/site no., name of the street, name of the enterprise etc., amendments can be carried out accordingly. But, if the change contemplated is consequent on the shifting of the entire unit to some other place/address, the existing license has to be surrendered and a new license has to be applied for.