Dear Querist,
I assume your query is only on TDS on Salaries. (Do you know TDS is also on various other payments made by your organization like interest, rent, professional fees, payment to contractors and sub-contractors, transports, commission, etc.)
It is not only about how to calculate, but also how to pay and how to file returns of TDS. You may be able to calculate with the help of the given link in normal cases, but please appreciate that there are different types of issues. For example, someone joins in between and wants you to include his previous employer's salary in the return or someone has some capital gains or other income/house property/ties, and so on.
If you are uninitiated in these subjects, you will end up on the wrong side of the law. It is better to consult your tax consultants/auditors, understand the fundamentals, or hire someone who knows.
A S Bhat