First, let me congratulate you on making a very good decision to get back to work. Many candidates are not able to take that very first step. From my experience working for an HR services company and dealing with client requirements, I can assure you that companies are very open and positive in hiring candidates who have come back after a long break as they bring a fresh lease of energy into the company. They are talented and do not come with any preconceived notions about the company. They make a great hire.
A Few Important Points:
1. Please don't compare yourself with any of your previous colleagues who continued their careers and insist on the same role/responsibility/compensation, etc. You should be open to working one scale up or down.
2. Speak to as many recruiters, ex-colleagues, and friends as possible and float your CV around on multiple job sites. Networking is very important.
3. Lastly, one very important point that I see a lot of candidates missing is adding new skills to their resume. Most candidates simply use their old CV and just add one or two new sentences and float it around. During your sabbatical, you might have added new skills, talents, and personality traits that need not be purely academic. Add these skills. They most certainly add weight to your resume.
Wishing you all the best,
Regards,
Kumar
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